Table 4
Pharmacokinetic parameters for muscle BTP level changes after intramuscular injection in olive flounder

Parameters	Units	13 ± 3 °C		22 ± 3 °C
Parameters	Units	50 mg/kg	150 mg/kg	50 mg/kg	150 mg/kg
k ₁₂	day⁻¹	2.103	2.406	2.178	1.474
k ₂₁	day⁻¹	0.322	0.462	0.196	0.553
C _max	mg/kg	1.662	4.428	1.456	3.219
T _max	days	0.150	0.121	0.246	0.071
t _1/2E	days	7.131	8.372	8.296	7.002
V _d	L	13.5	23.743	13.477	40.826
V _d2	L	149.466	123.763	149.466	108.798
Cl	L/day	19.171	14.452	22.863	17.160
AUC _0-∞	mg/kg·day	2.608	10.379	2.187	8.741
AUCM	mg/kg·day²	19.725	106.512	16.086	76.403
MRT _0-∞	days	7.563	10.262	7.356	8.740